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“Our target is to be familiar with feminine reproductive growing older, and why fertility speedily declines starting during the mid-30s,” suggests Satoshi Namekawa, a professor of Microbiology and Molecular Genetics, in whose lab Munakata operates.
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This allows the oocytes to pause their growth and enter a Keeping pattern, which lasts in to the mouse’s adulthood. In mice missing PRC1, the oocytes didn’t pause their advancement; in its place, they withered and died in just a month, leaving the mice forever infertile.
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The grant from the worldwide Consortium for Reproductive Longevity and Fairness (GCRLE) was announced in June. It can supply $two hundred,000 in funding, spread about two a long time. With it, Munakata will examine just a little-regarded element of reproductive biology: just how an egg mobile stops growing and enters a holding pattern, proper round the time a feminine is born.
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